Quick Search
  Home Journal Information Current Issue Past Issues Services Contact Us  
Articles
Psychomotor development of children born after preimplantation genetic diagnosis and parental stress evaluation 
 
Psychomotor development of children born after preimplantation genetic diagnosis and parental stress evaluation
  Loretta Thomaidis, Sophia Kitsiou-Tzeli, Elena Critselis, Hera Drandakis, Vassiliki Touliatou, Stelios Mantoudis, Eleni Leze, Aspasia Destouni, Joanne Traeger-Synodinos, Dimitrios Kafetzis, Emmanouel Kanavakis
 [Abstract] [Full Text] [PDF]   Pageviews: 10377 Times
   

Author Affiliations: Developmental Assessment Unit, Second Department of Pediatrics, "P. & A. Kyriakou" Children's Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece (Thomaidis L, Critselis E, Drandakis H, Mantoudis S, Kafetzis D); Department of Medical Genetics, National and Kapodistrian University of Athens School of Medicine, Athens, Greece (Kitsiou-Tzeli S, Touliatou V, Leze E, Destouni A, Traeger-Synodinos J, Kanavakis E)

Corresponding Author: Loretta Thomaidis, MD, PhD, Developmental Pediatrics, Developmental Assessment Unit, Second University Department of Pediatrics, "P. & A. Kyriakou", Children's Hospital, Livadias and Thivon Streets, Athens 11527, Greece (Tel: +302132009198; Fax: +302107774383; Email: dr_thomaidis@yahoo.gr)

doi: 10.1007/s12519-012-0374-0

Background: The increasing number of children conceived following preimplantation genetic diagnosis (PGD) necessitates the evaluation of their motor and cognitive development. The primary study objective was to evaluate the physical, developmental, and neurological outcome of children born after PGD in Greece. In addition, the secondary study objective was to compare the stress levels regarding parental roles between parents of PGD children and those of naturally conceived children.

Methods: A cross-sectional study design was applied. The study population consisted of 31 children (aged 2 months to 7.5 years) born after PGD analysis and their parents. The developmental evaluation of children included a detailed physical evaluation and cognitive assessment with the Bayley Scales of Infant Development. The parent stress index was applied to evaluate comparative parental stress levels between those parents of PGD children and those of naturally conceived healthy children.

Results: High rates of caesarean deliveries, increased incidence of prematurity, multiples and low-birth weight were observed among the 31 PGD children. Overall, 24 of the 31 PGD children had cognitive skills within normal range [general developmental quotient (GDQ): 86-115], while 6 children had lower levels of cognitive skills (GDQ<85). With regard to parental stress, PGD parents reported lower levels of parenting stress as compared to parents of naturally conceived children (P<0.01).

Conclusions: The enhanced frequency of poor cognitive and motor skills as well as low parental stress necessitates early detection and intervention for developmental delays among PGD children.

Key words: general developmental quotient; parental stress level; preimplantation genetic diagnosis; psychomotor development

World J Pediatr 2012;8(4):309-316

 
  [Articles Comment]

  title Author The End Revert Time Revert / Count

  Username:
  Comment Title: 
 
   

 

     
 
     
World Journal of Pediatric Surgery

roger vivier bags 美女 美女

Home  |  Journal Information  |  Current Issue  |  Past Issues  |  Journal Information  |  Contact Us
Children's Hospital, Zhejiang University School of Medicine, China
Copyright 2007  www.wjpch.com  All Rights Reserved Designed by eb