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Mesalamine treatment mimicking relapse in a child with ulcerative colitis
Iva Hojsak, Ana M Pavić, SanjaKolaček
Zagreb, Croatia
Author Affiliations: Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Zagreb, Croatia (Hojsak I, MočićPavić A, Kolaček S); University of Zagreb Medical School, Zagreb, Croatia (Hojsak I, Kolaček S)
Corresponding Author: Iva Hojsak, MD, PhD, Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, Klaićeva 16, Zagreb, Croatia (Tel: +385-1-4600130; Fax: +385-1-4600160; Email: ivahojsak@gmail.com)
doi: 10.1007/s12519-014-0485-x
Background: There are reports on mesalamine-induced bloody diarrhea mimicking ulcerative colitis (UC) relapse, mostly in adults.
Methods: Herein we present a case of a child with UC who developed relapse of hemorrhagic colitis related to mesalamine.
Results: A 10-year-old girl developed severe symptoms mimicking UC relapse 3 weeks after introduction of mesalamine therapy. After mesalamine was withdrawn, her symptoms improved, but deteriorated again during the challenge of mesalamine despite concomitant use of corticosteroids.
Conclusion: This is the first case report on such a young child during the concomitant use of corticosteroids.
World J Pediatr 2014;10(4):371-373
Key words: 5-aminosalicylic acid;
mesalamine; ulcerative colitis
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